夏咏梅

【学术简介】

学习经历
1980-1984南京化工学院无锡分院，有机化工本科

1984-1986无锡轻工业学院化工学院，轻工有机合成专业硕士

2000-2002无锡轻工业大学生物工程学院，酶工程专业博士

工作经历
1987-1997无锡轻工业学院化学工程系助教、讲师

1998-2002无锡轻工业学院（无锡轻工业大学）化学工程系，副教授

2002-2005美国密歇根大学，化学工程系II级研究员
2003-至今江南大学化工学院化学工程系教授、博导，食品科学与技术国家重点实验室教授、博导

【研究领域】

运用化工过程、胶体与界面化学和生物化学研究表面活性剂（包括表面活性食品添加剂）的绿色合成及应用，特别是绿色和天然非离子表面活性剂如烷基醇醚、糖苷的合成，天然产物酶促和化学改性及其产物的溶液界面化学行为，生物活性及其在化妆品和食品中的应用。

【科研项目】

近5年来主持国家自然科学基金项目、科技部重点专项项目、国家科技支撑项目和其它省部级课题等10余项。其中代表性课题如下:

1.国家重点研发计划项目: “绿色安全型表面活性剂”之课题五“脂肪酸囊泡的囊材生产技术开发(2017YFB0308705)”, 2017年7月-2021年7月

2.国家自然科学基金面上项目：甜菊糖苷及其代谢产物对典型维生素生物有效性和生物利用度的影响及作用机制(31772017)，2018年1月-2021年12月

3.科技部工业支撑计划项目：功能性表面活性剂绿色制备与产业化示范(2014BAE03B01)，2014年1月-2016年12月

4.国家自然科学基金面上项目：基于生物转化和代谢分析构建非营养高倍甜味剂斯梯夫苷系的代谢产物谱(31371837)，2014年1月-2017年12月

5.国家自然科学基金面上项目：功能性甜菊糖苷的酶法制备及其分子识别机制研究(31171752)，2012年1月-2015年12月

【科研成果及荣誉】

2014年和2013年两获江苏省科技进步三等奖；2012年中国教育部科技进步一等奖；2007年中国轻工业联合会进步1等奖；2006年入选教育部新世纪优秀人才支持计划；2003年省优秀青年教师；2001年省优秀博士论文。
【学术兼职】

中国洗协表面活性剂专业委员会委员;

中国甜菊协会副理事长；

国内期刊《中国洗涤用品工业》和《中国油脂化工》的编委；

国际期刊“Bioactive Carbohydrates and Dietary Fibre”、“Journal of Korean Clinical Health Science”和“International Journal of Functional Nutrition”的编委。

【主要论著】

共发表SCI论文100余篇，完成专著1部。授权发明专利30项，其中国际授权发明专利2项。代表性论文如下:

1. Myint KZ, Wu K, Xia Y, Fan Y, Shen J, Zhang P, et al. Polyphenols from Stevia rebaudiana (Bertoni) leaves and their functional properties. J Food Sci. 2020;85(2):240-8.

2. Guo Q, Zhang T, Wang N, Xia Y, Zhou Z, Wang JR, et al. RQ3, A Natural Rebaudioside D Isomer, Was Obtained from Glucosylation of Rebaudioside A Catalyzed by the CGTase Toruzyme 3.0 L. Journal of Agricultural and Food Chemistry. 2019;67(28):8020-8.

3. Guo L, Yang J, Guo X, Xia Y. Self-assembled vesicles of sodium oleate and chitosan quaternary ammonium salt in acidic or alkaline aqueous solutions. Colloid Polym Sci. 2019;297(11-12):1455-63.

4. Fan Y, Liu T, Fang Y, Xia Y. Vesiculation and Stability: Oligomer of Conjugated Linoleate Acids Prepared by High Internal Phase Self-emulsion Polymerization. Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao. 2019;40(6):1193-200.

5. Chen J, Hu XY, Fang Y, Liu HH, Xia YM. Comparative Study of Conventional/Ethoxylated/Extended n-Alkylsulfate Surfactants. Langmuir. 2019;35(8):3116-25.

6. Chen J, Hu XY, Fang Y, Jin GY, Xia YM. What dominates the interfacial properties of extended surfactants: Amphipathicity or surfactant shape? J Colloid Interface Sci. 2019;547:190-8.

7. Chen C, Su L, Xu F, Xia Y, Wu J. Improved Thermostability of Maltooligosyltrehalose Synthase from Arthrobacter ramosus by Directed Evolution and Site-Directed Mutagenesis. Journal of Agricultural and Food Chemistry. 2019;67(19):5587-95.

8. An ZZ, Zhou ZY, Xia YM, Xin D, Hu XY, Fang Y. Modulating Water Absorption of Hardened Gypsum Plaster with Enhanced Mechanical Strengths by Molecular Modification of Polyvinyl Alcohol. J Mater Civ Eng. 2019;31(11).

9. Liu Y, Tang Q, Zhang J, Xia Y, Yang Y, Wu D, et al. Triple helix conformation of β-D-glucan from Ganoderma lucidum and effect of molecular weight on its immunostimulatory activity. Int J Biol Macromol. 2018;114:1064-70.

10. Hou C, Cui W, Wu S, Xia Y. Covalent linkage of casein hydrophobic peptide to gum Acacia seyal and surface physicochemical properties of the products. J Food Sci Biotechnol. 2018;37(4):385-91.

11. Fan Y, Zheng Y, Fang Y, Xia Y, Gao D, Wang J. Vesiculation of Sodium Conjugated Linoleate in Alkaline Conditions Induced by Oligomerization. Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao. 2018;39(7):1483-9.

12. Fan Y, Ma J, Fang Y, Liu T, Hu X, Xia Y. Neutral and acid-adapted fatty acid vesicles of conjugated linoleic acid. Colloids Surf B Biointerfaces. 2018;167:385-91.

13. Chen JM, Zhang J, Xia YM, Wang XX, Li J. The natural sweetener metabolite steviol inhibits the proliferation of human osteosarcoma U2OS cell line. Oncol Lett. 2018;15(4):5250-6.

14. Chen JM, Xia YM, Zhang YD, Zhang TT, Peng QR, Fang Y. Influence of substrates on the in vitro kinetics of steviol glucuronidation and interaction between steviol glycosides metabolites and UGT2B7. Int J Food Sci Nutr. 2018;69(4):472-9.

15. Chen J, Xia Y, Sui X, Peng Q, Zhang T, Li J, et al. Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively. Oncotarget. 2018;9(41):26299-308.

16. Su L, Ji D, Tao X, Yu L, Wu J, Xia Y. Recombinant expression, characterization, and application of a phospholipase B from Fusarium oxysporum. J Biotechnol. 2017;242:92-100.

17. Liang X, Fan Y, Fang Y, Xia Y, Cheng R. Investigation of Vesiculation of Conjugated Linoleic Acid Assisted by Monolauryl Phosphate. Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao. 2017;38(9):1639-44.

18. Hou C, Wu S, Xia Y, Phillips GO, Cui SW. A novel emulsifier prepared from Acacia seyal polysaccharide through Maillard reaction with casein peptides. Food Hydrocolloids. 2017;69:236-41.

19. Zhou PP, Wu HC, Xia YM. Influence of synthetic polymers on the mechanical properties of hardened β-calcium sulfate hemihydrate plasters. J Ind Eng Chem. 2016;33:355-61.

20. Zhang J, Chen JM, Wang XX, Xia YM, Cui SW, Li J, et al. Inhibitor or promoter? the performance of polysaccharides from: Ganoderma lucidum on human tumor cells with different p53 statuses. Food Funct. 2016;7(4):1872-5.

21. Sui XC, Guo QB, Xia YM, Cui SW, Shen J, Zhang J, et al. Structure features of the intracellular polysaccharide from Ganoderma lucidum and the irrelative immune-anticancer activities of GLPs. Bioact Carbohydr Dietary Fibre. 2016;8(2):43-50.

22. Su L, Hong R, Guo X, Wu J, Xia Y. Short-chain aliphatic ester synthesis using Thermobifida fusca cutinase. Food Chem. 2016;206:131-6.

23. Liu Y, Zhang J, Tang Q, Yang Y, Xia Y, Zhou S, et al. Rheological properties of β-d-glucan from the fruiting bodies of Ganoderma lucidum. Food Hydrocolloids. 2016;58:120-5.

24. Chen JM, Ding L, Sui XC, Xia YM, Wan HD, Lu T. Production of a bioactive sweetener steviolbioside via specific hydrolyzing ester linkage of stevioside with a b-galactosidase. Food Chem. 2016;196:155-60.

25. Zhang YD, Li W, Lu T, Xia YM. The effect of microwave irradiation on transglycosylation pathway of stevioside with starches or cyclodextrins catalyzed by a cyclodextrin glucanotransferase. J Mol Catal B Enzym. 2015;120:151-7.

26. Xia XF, Gu Z, Liu W, Wang H, Xia Y, Gao H, et al. Metal-free three-component oxyazidation of alkenes with trimethylsilyl azide and N-hydroxyphthalimide. J Org Chem. 2015;80(1):290-5.

27. Wan HD, Xia YM. Enzymatic transformation of stevioside using a β-galactosidase from Sulfolobus sp. Food Funct. 2015;6(10):3291-5.