一、个人简介
李瑞怡,女,1991年4月出生,博士、副研究员、硕士生导师。
主要经历:
2022.01~至今江南大学生命科学与健康工程学院副研究员
2019.01~2022.01 江南大学药学院副研究员
2015.09~2018.12 江南大学化学工程与技术工学博士学位
2016.08~2017.08 加拿大多伦多大学生物分析国家公派博士联合培养
2013.09~2014.09 英国伯明翰大学药物研发与药物化学理学硕士学位
2012.09~2013.06 爱尔兰国立大学梅努斯制药化学理学学士学位
2009.09~2012.06 常州大学化学工程与工艺工学学士学位
二、研究领域
1.高性能三维石墨烯材料的构筑、功能化及在生物分析中的应用。
2.上转换发光材料与石墨烯量子点复合,及对癌症的诊疗一体化研究。
3.生物快速检测与药物光控释放。
4.亲生物性材料,医用敷料
三、荣誉奖励
李在均,瞿研,王光丽,顾志国,李瑞怡,蔡燕,石墨烯工业制备关键技术开发与应用,中国轻工业联合会科学技术发明奖,三等奖,2017。
四、学术成果
(一)代表性项目
1.教育部直属高校科研项目,基于宫颈癌精准医疗的石墨烯量子点-稀土上转换纳米载药体系研究
2.中国博士后科学基金第70批面上资助
3.企业横向课题三项
(二)代表性论文
1.Li Ruiyi, Jia Hui, Li Nana, Xu Dan, Li Zaijun, Electrochemical detection of chlorpyrifos in fruits with gold-histidine functionalized graphene quantum dot-graphene hybrid and target-induced DNA cycle amplification,Sens. Actuator B-Chem., 2022, 355, 131314.
2.Li Ruiyi, Wang Jin, Li Nana, Xu Dan, Li Zaijun, Electrochemical detection of omethoate and acetamiprid in vegetable and fruit with high sensitivity and selectivity based on pomegranate-like gold nanoparticle and double target-induced DNA cycle signal amplification,Sens. Actuator B-Chem.,2022, 359, 131597.
3.Li Ruiyi, Wang Xiaobo, Peng Yuanfeng, Xu Pengwu, Zhu Haiyan, Li Zaijun, Sun Xiulan, Synthesis of gold nanocrystals with chiral morphology, chiral ligand and more exposed high-index facets as electrocatalyst for the oxidation of glucose enantiomers with high enantioselectivity and catalytic activity,Catal. Sci. Technol., 2022, DOI: 10.1039/d1cy01764k.
4.Li Ruiyi, Zhang Huahua, Li Zaijun, Switchable two-color graphene quantum dot as a promising fluorescence probe to highly sensitive pH detection and bioimaging,Spectrochim. Acta, Part A, 2022, 121028.
5.Li Ruiyi, He Keyang, Yang Yongqiang, Zhu Haiyan, Li Zaijun, Atomically dispersed RuO2-tryptophan functionalized graphene quantum dot-graphene hybrid with double Schottky heterojunctions for high performance flexible supercapacitors,Chem. Eng. J., 2021, 426.
6.Li Ruiyi, He Keyang, Xu Pengwu, Wang Wendong, Li Nana, Zhu Haiyan, Li Zaijun, Liu Xiaohao Synthesis of a ruthenium-graphene quantum dot-graphene hybrid as a promising single-atom catalyst for electrochemical nitrogen reduction with ultrahigh yield rate and selectivity,J. Mater. Chem. A, 2021, 9, 24582-24589.
7.Li Ruiyi, Jiang Yanhong, Wang Qinsheng, Yang Yongqiang, Li Nana, Sun Xiulan, Li Zaijun, Serine and histidine-functionalized graphene quantum dot with unique double fluorescence emission as a fluorescent probe for highly sensitive detection of carbendazim,Sens. Actuator B-Chem.,2021, 343.
8.Li Ruiyi, Li Zaijun, Sun Xiulan, Ji Jan, Liu Lin, Gu Zhiguo, Wang Guangli, Graphene quantum dot-rare earth upconversion nanocages with extremely high efficiency of upconversion luminescence, stability and drug loading towards controlled delivery and cancer theranostics,Chem. Eng. J., 2020, 382.
9.Li Ruiyi, Pu Tinling, Chu Hongxia, Shi Jinsong, Li Zaijun, Electrochemical detection of cancer cells in human blood using folic acid and glutamic acid-functionalized graphene quantum dot-palladium@gold as redox probe with excellent electrocatalytic activity and target recognition,Sens. Actuator B-Chem.,2020, 309.
10.Li Ruiyi, Cui Fangchao, Zhu Haiyan, Sun Xiulan, Li Zaijun Electrochemical sensor for detection of cancer cell based on folic acid and octadecylamine-functionalized graphene aerogel microspheresBiosens. Bioelectron., 2018, 119, 156-162.
11.Li Ruiyi, Li Zaijun, Wang Guangli, Gu Zhiguo, Octadecylamine-functionalized graphene vesicles based voltammetric sensing of hydroquinone, Sens.Actuator B-Chem., 2018, 276, 404-412.
12.Li Ruiyi, Liu Ling, Zhu Haiyan, Li Zaijun, Synthesis of gold-palladium nanowaxberries/dodecylamine-functionalized graphene quantum dots-graphene micro-aerogel for voltammetric determination of peanut allergen Ara h 1,Anal. Chim. Acta, 2018, 1008, 38-47.
13.Li Ruiyi, Zhu Haiyan, Li Zaijun, Liu Junkang, Electrochemical determination of acetaminophen using a glassy carbon electrode modified with a hybrid material consisting of graphene aerogel and octadecylamine-functionalized carbon quantum dots,Microchim. Acta, 2018, 185, 2.
14.Li Ruiyi, Li Zaijun, Liu Junkang, Histidine-functionalized carbon-based dot-Zinc(II) nanoparticles as a novel stabilizer for Pickering emulsion synthesis of polystyrene microspheres,J. Colloid Interface Sci.,2017, 493, 24-31.
15.Li Ruiyi, Qing Sili, Li Zhangyi, Liu Ling, Li Zaijun, Histidine-functionalized graphene quantum dot-graphene micro-aerogel based voltammetric sensing of dopamine,Sens. Actuator B-Chem.,2017, 250, 372-382.
16.Li Ruiyi, Yang Tingting, Li Zaijun, Gu Zhiguo, Wang Guangli, Liu Junkang, Synthesis of palladium@gold nanoalloys/nitrogen and sulphur-functionalized multiple graphene aerogel for electrochemical detection of dopamine,Anal. Chim. Acta, 2017, 954, 43-51.
17.Li Ruiyi, Liu Ling, Li Zaijun, Gu Zhiguo, Wang Guangli, Liu Junkang, Graphene micro-aerogel based voltammetric sensing of p-acetamidophenol,Microchim. Acta, 2017, 184, 1417-1426.
(三)主要授权专利
1.一种石墨烯-稀土上转换符合纳米微球的制备方法及其应用,李瑞怡,李在均,刘玲,CN 110624116 B
2.荧光增强型石墨烯量子点-下转换稀土氟化物复合材料,李在均,刘玲,李瑞怡,ZL 2018 1 0218688.9
3.一种功能化石墨烯气凝胶微球的制备方法,李在均,李瑞怡,ZL 2018 1 0218703.X
五、联系方式
通讯地址:江苏省无锡市蠡湖大道1800号江南大学生命科学与健康工程学院
邮编:214122
邮箱:jessicamegy@qq.com
【以上资料更新日期】:2022年3月