Basic Information

Title: Professor

Office: 713 Jiangnan University Synergetic Innovation Center

Email: zhouzhi@jiangnan.edu.cn.

Main Experiences

2007-2011 Harbin University of Science and Technology, Pharmaceutical Engineering, Bachelor

2011-2014 West China School of Pharmacy，Sichuan University，Department of medicinal chemistry，Master

2014-2017West China School of Pharmacy，Sichuan University，Department of medicinal chemistry，Doctor

2017-2021 University of Groningen, Department of Chemistry, Postdoc

2021.09-presentJiangnan University, School of Life Sciences and Health Engineering, Professor

Research Areas

The main research direction of Zhou is artificial enzymes, for example, through biological and chemical techniques, new artificial enzymes can be efficiently constructed to achieve unnatural reactions catalyzed by artificial enzymes. It realizes unnatural reactions catalyzed by artificial enzymes, clarifies the mechanism of new enzymatic catalyzed reactions and expands the scope of enzymatic catalyzed reactions and the application of enzymes in synthetic biology. In recent years, he has published a number of high level papers in international authoritative academic journals, including Nature Catalysis, Nature Chemistry, ACS Catalysis, Angew. Chem. Int. Ed, etc.

Awards and Hornors

(1) Jiangsu Distinguished Professor, 2022

(2) Wuxi "Taihu Talent Plan" innovation leader, 2022

(3) Jiangnan University "Best Young Scholars" Support Program, 2022

Research Projects within five years

(1) National Key Research and Development Plan "Synthetic Biology" key special youth project, 2022-2026

(2) National Natural Science Foundation of China Youth Project, 2023-2025

(3) Youth Project of Jiangsu Natural Science Foundation, 2022-2025

Publications within five years

[1]Z. Zhou, G. Roelfes^#. Synergistic catalysis in an artificial enzyme by simultaneous action of two abiological catalytic sites,Nature Catalysis.2020, 3, 289.

[2]Z. Zhou,et al.YC. Chen^#. Switchable regioselectivity in amine-catalysed asymmetric cycloadditions,Nature Chemistry.2017, 9, 590.

[3]Z. Zhou^#, G. Roelfes^#. Synergistic Catalysis of Tandem Michael Addition / Enantioselective Protonation Reactions by an Artificial Enzyme,ACS Catalysis.2021, 11, 9366.

[4] L. O. Atta^#,Z. Zhou^#, G. Roelfes^#. In Vivo Biocatalytic Cascades Featuring an Artificial Enzyme Catalyzed New-to-Nature Reaction,Angew. Chem. Int. Ed.2023, 10.e202214191.

[5]Z. Zhou,et al.YC. Chen^#, Double Thiol-Chiral Brønsted Base Catalysis: Asymmetric Cross Rauhut–Currier Reaction and Sequential [4 + 2] Annulation for Assembly of Different Activated Olefins,Organic Letters.2019, 21, 7184.