Gender

Male

Date of birth

1979.1

Professional Title

Professor

Tel

E-mail

junlin@jiangnan.edu.cn

【Education background】

2009.12, Ph.D.Fermentationengineering, Jiangnan University, Wuxi, China.

2000.7, Bachelor, Biotechnology, Jiangnan University, Wuxi, China.

【Professionalexperience】

2022.01- present, Professor, School of Life Science and Health Engineering, 18新利体育备用网址

2018.06-2022.01, Professor, School of Pharmacy, 18新利体育备用网址

2012.03 -2018.06, PI,ShanghaiInstituteofPharmaceuticalIndustry.

2009.12 -2012.03, Postdoctoral Fellow,ShanghaiInstituteofPharmaceuticalIndustry.

2002.03-2005.03, Yantai Medgenn Co., Ltd.

2000.07-2002.03, Yantai Beer Asahi Co., Ltd.

【Research Interests】

New drug research and development, research in synthetic biology.

【Selected Publications】

[1] P. Lin, Z. Chen,J. Lin, Therapeutic drugs of gout: The progress in target selection, Int J Rheum Dis (2023) e15022.

[2] P. Lin, D. Zhang,J. Lin, Clinical Research Progress of BTK Inhibitors in the Treatment of Autoimmune Diseases, Curr Top Med Chem 23 (2023) 2609-2620.

[3] P. Lin, H.Y. Shi, Y.Y. Lu,J. Lin, Centella asiatica alleviates psoriasis through JAK/STAT3-mediated inflammation: An in vitro and in vivo study, J Ethnopharmacol 317 (2023) 116746.

[4]J. Lin, L.Y. Yang, Z.D. Pan, Identification of Potential Bioactive Compounds from Aspergillus terreus against HCV NS3 Serine Protease, Chem Biodivers 20(8) (2023) e202300532.

[5]J. Lin, Y.Y. Lu, H.Y. Shi, P. Lin, Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), Polysaccharides Alleviate Photoaging by Regulating Nrf2 Pathway and Autophagy, Int J Med Mushrooms 25(10) (2023) 49-64.

[6] S. Chen, Z. Chen, L. Lu, Y. Zhao, R. Zhou, Q. Xie, Y. Shu,J. Lin, X. Yu, Y. Wang, Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy, Eur J Med Chem 255 (2023) 115403.

[7] M. Hong, K. Xiao, P. Lin,J. Lin, Five Rutaceae family ethanol extracts alleviate H(2)O(2) and LPS-induced inflammation via NF-κB and JAK-STAT3 pathway in HaCaT cells, Chin J Nat Med 20(12) (2022) 937-947.

[8] B.X. Du, P. Lin,J. Lin, EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells, Chin J Nat Med 20(4) (2022) 290-300.

[9] Y. Zhao, Y. Shu,J. Lin, Z. Chen, Q. Xie, Y. Bao, L. Lu, N. Sun, Y. Wang, Discovery of novel BTK PROTACs for B-Cell lymphomas, Eur J Med Chem 225 (2021) 113820.

[10] S. Liu, Y. Da, F. Wang, R. Yan, Y. Shu, P. Lin,J. Lin, Targeted selective degradation of Bruton’s tyrosine kinase by PROTACs, Med. Chem. Res. 29(4) (2020) 802-808.

[11] Y. Da, S. Liu, P. Lin, F. Wang, R. Yan, Y. Shu,J. Lin, Design, synthesis, and biological evaluation of small molecule PROTACs for potential anticancer effects, Med. Chem. Res. 29(2) (2020) 334-340.