Education and Experience：

Sep.1991-July 1995, School of biotechnology, Jiangnan University，Bachelor of Engineering;

Aug.1995-July 2009, School of biotechnology, Jiangnan University，Research assistant;

Mar.1999-Apr.2002,School of biotechnology, Jiangnan University, Master of engineering;

Aug.2009-present, School of Life Sciences and Health Engineering, Jiangnan University，Associate professor。

Research fields:

1.Study on the mammalian cell lines for biopharmaceutical production

2.Study on the mechanism of multidrug resistance in tumor

3.Study on the pharmacokinetics and drug quality standard

Selected publications:

[1]Breast cancer resistance protein(BCRP)-containing circulating microvesicles contribute to chemoresistance in breast cancer.Oncology Letters2015,10:3742-8

[2] Crystallization and preliminary X-ray diffraction analysis of an endo-1,4-β-D-glucanase from Aspergillus aculeatus F-50. Acta Cryst.2015, F71: 397-400

[3] Development and characterization of monoclonal antibodies against pancreatic cancer marker hippocalcin-like 1 protein. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 2014, 33: 20-7

[4] A comprehensive screening method for investigating the potential binding targets of doxorubicin based on protein microarray. European Journal of Pharmacology. 2021, online

[5] Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells. Proc Natl Acad Sci USA 2012, 109:16282-7

[6] Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance. Proc Natl Acad Sci USA 2014, 111 : 6389-94

[7] USE OF GENOMIC NW_006880285.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN，United States Patent, US11692204 B2

[8] USE OF GENOMIC NW_006882077.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN，United States Patent, US11732276 B2

[9] USE OF NW_003613638.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEIN，Singapore patent, 11202009389Q

[10] USE OF NW_006882456.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEINS，United States Patent, 11202010741W