JingWu, AssociateProfessor

School of Pharmaceutical Sciences, Jiangnan University

No. 1800 Lihu Avenue, Wuxi, jiangsu, RPC

E-Mail:wujing@jiangnan.edu.cn

Education

May2013–Jun. 2014	Postdoc.	Northwestern University,USA Department of Chemical and Biological Engineering
Sep. 2003–Sep. 2008	Ph.D.	Jiangnan University, China School of Biotechnology
Sep.1999–Jun. 2003	B.S.	Jiangnan University, China School of Biotechnology

Work Experience

Jan. 2017- Now	Associate Professor	Jiangnan University School of Pharmaceutical Sciences
Sep. 2012–Dec. 2016	Associate Professor	Jiangnan University Wuxi Medical School
Oct. 2008– Aug. 2012	Lecturer	Jiangnan University School of Medicine and Pharmaceutics

Area of Research

1.Production ofpharmaceutical intermediatesby biotechnology.

2.Enzyme discovery, reconstruction and application.

ResearchProjects

1.National Natural Science Foundation of China (21576117),Mechanism of metal ions regulating theprocessivity and fidelityof Y family polymerase Dpo4.

2.National Natural Science Fund Youth Fund (31101229),Molecular modificationon theheat / alkali resistanceof xylanasefromAspergillus oryzae.

3.the branch project ofChinese High-tech R&DProgram(863)(2012AA022 108), Genome engineering improves the production of pharmaceutical proteins byBacillus subtilis.

4.Key research and development plan of Jiangsu Province(BE2015307),Study on the key technology of microbial preparation of vitamin C phosphate.

Journal Publications

1. Zhang Q, Yao R, Chen X, Liu L, Xu S, Chen J,Wu J*. Enhancing fructosylated chondroitin production in Escherichia coli K4 by balancing the UDP-precursors.Metab Eng. 2018, 47:314-322.

2.Wang L, Liang C,Wu J*, Liu L, Tyo KEJ. Increased Processivity, Misincorporation, and Nucleotide Incorporation Efficiency in Sulfolobus solfataricus Dpo4 Thumb Domain Mutants.Appl Environ Microbiol. 2017,83(18). pii: e01013-17.

3.Zheng K, Song W, Sun A, Chen X, Liu J, Luo Q,Wu J*. Enzymatic Production of Ascorbic Acid-2-phosphate by Recombinant Acid Phosphatase.J Agric Food Chem. 2017, 65(20):4161-4166.

4.Wu J, Wang H, Yang B, Song W, Liang C, Liu L. Efficient production of (R)-3-TBDMSO glutaric acid methyl monoester by manipulating the substrate pocket of Pseudozyma antarctica lipase B.RSC Adv., 2017, 7, 38264-38272

5. Yun J, Duan F, Liu L, Chen X, Liu J, Luo Q, Wu J*. A selective and sensitive nanosensor for fluorescent detection of specific IgEs to purified allergens in human serum.RSC Adv., 2018,8(7): 3547-3555.

6.Wu J, de Paz A, Zamft BM, Marblestone AH, Boyden ES, Kording KP, Tyo KEJ. DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase.Sci Rep. 2017,7(1):4756.

7.Wang Y, Xu N, Ye C, Liu L, Shi Z,Wu J*. Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production.Front Microbiol. 2015,6:632.

8.Luo Q,Wu J*, Wu M. Enhanced acetoin production by Bacillus amyloliquefaciens through improved acetoin tolerance,Process Biochemistry,2014,49:1223-1230

9.Zhang Y, Li S, Liu L,Wu J*. Acetoin production enhanced by manipulating carbon flux in a newly isolated Bacillus amyloliquefaciens.Bioresour Technol. 2013 ,130: 256-260.