Bio

Dr. Jun HU was born in 1990 in Sichuan , China. He obtained his B.S. in Chemistry in 2014 and later a Ph.D. in Analytical Chemistry (specialized in Mass Spectrometry) in 2019 from Nanjing University with Prof. Jing-Juan XU. After postdoctoral work with Prof. Yun Chen at Nanjing Medical University from 2019 to 2021, he moved to Jiangnan University to start his independent career in 2022. His research focuses on the developments of advanced mass spectrometric techniques for (bio)chemistry and clinical medicine. Positions are available in his lab, probably two for master's degrees and one for doctoral degree every year.

Research Interests

My research goal is to develop advanced mass spectrometric techniques for (bio)chemistry and clinical medicine. I am particularly interested in developing low-delay MS methods for capturing and identifying the transient and fragile intermediates in electrocatalytic, photocatalytic and enzyme catalytic reactions, to gain in-depth understanding of reaction mechanism as well as rationalize designs of sustainable reactions. I am currently also interested in developing high-throughput MS methods for clinical analysis, with the objective of early diagnosis of diseases and fundamental insights into pathogenesis.

Publications

Associated Professor at JNU（since 2022.08）

[15] Coming soon…

[14] Chun-Yan Liu, Yun Chen*,Jun Hu*, Identification of the electrogenerated hidden nitrenium ions by in situ mass spectrometry[J]. Analytical Chemistry, 2024, 96 (8): 3354-3361.

[13] Hang Gao, Shen-Yu Shi, Shu-Min Wang, Qian-Qian Tao, Hui-Li Ma*,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, Aggregation‐induced delayed electrochemiluminescence of organic dots in aqueous media[J]. Aggregate, 2024, 5(1): e394.

[12] Ting Wang, Qiu-Yue Cheng,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, Capture and identification of the electrogenerated picosecond intermediates by mass spectrometry[J]. Fundamental Research, 2023. DOI: 10.1016/j.fmre.2023.08.016

[11] Ting Wang, Zheng Li, Hang Gao,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, Ultrafast C–C and C–N bond formation reactions in water microdroplets facilitated by the spontaneous generation of carbocations[J]. Chemical Science, 2023, 14 (41): 11515-11520.

[10] Qiu-Yue Cheng, Ting Wang,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, In situ probing the short-lived intermediates in visible-light heterogeneous photocatalysis by mass spectrometry[J]. Analytical Chemistry, 2023, 95 (37): 14150-14157.

Short stay at NJU (2022.03-2022.09)

[9] Wen Lei,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, Nanopore liberates g-quadruplexes from biochemical buffers for accurate mass spectrometric examination[J]. Analytical Chemistry, 2022, 94 (51): 17972-17979.

[8] Wen Lei,Jun Hu*, Hong-Yuan Chen, Jing-Juan Xu*, Combined strategies for suppressing nonspecific cationic adduction to G-quadruplexes in electrospray ionization mass spectrometry[J]. Analytica Chimica Acta, 2022, 1220: 340146. [Cover Story]

[7] Xiao-Jun Xi,Jun Hu,* Hong-Yuan Chen, Jing-Juan Xu,* Rapid identification of the short-lived intermediates in alternating-current electrolysis by mass spectrometry[J], Chemical Communications, 2022, 58(73): 10233-10236.

Postdoc (2019.11-2021.11) & Associated Professor (2022.01-2022.06) at NJMU

[6]Jun Hu, Ting Wang, Wen-Jun Zhang, Han Hao, Qiao Yu, Hang Gao, Nan Zhang, Yun Chen*, Xing-Hua Xia, Hong-Yuan Chen, Jing-Juan Xu*, Dissecting the flash chemistry of electrogenerated reactive intermediates by microdroplet fusion mass spectrometry[J]. Angewandte Chemie International Edition, 2021, 60 (34): 18494-18498. [Hot Paper]

[5]Jun Hu, Nan Zhang, Pan-Ke Zhang, Yun Chen, Xing-Hua Xia, Hong-Yuan Chen, Jing-Juan Xu, Coupling a wireless bipolar ultramicroelectrode with nano-electrospray ionization mass spectrometry: insights into the ultrafast initial step of electrochemical reactions[J]. Angewandte Chemie International Edition, 2020, 59 (41): 18244-18248.

Ph.D. at NJU（2014.09-2019.09）

[4]Jun Hu, Wen Lei, Jiang Wang, Hong-Yuan Chen, Jing-Juan Xu*, Preservation of protein zwitterionic states in the transition from solution to gas phase revealed by sodium adduction mass spectrometry[J]. Analytical Chemistry, 2019, 91 (12): 7858-7863.

[3]Jun Hu‡, Wen Lei‡, Jiang Wang, Hong-Yuan Chen, Jing-Juan Xu*, Regioselective 5′-position phosphorylation of ribose and ribonucleosides: phosphate transfer in the activated pyrophosphate complex in the gas phase[J]. Chemical Communications, 2019, 55 (3): 310-313. (‡equal contribution)

[2]Jun Hu, Qi-Yuan Guan, Jiang Wang, Xiao-Xiao Jiang, Zeng-Qiang Wu, Xing-Hua Xia, Jing-Juan Xu*, Hong-Yuan Chen, Effect of nanoemitters on suppressing the formation of metal adduct ions in electrospray ionization mass spectrometry[J]. Analytical Chemistry, 2017, 89 (3): 1838-1845.

[1]Jun Hu, Xiao-Xiao Jiang, Jiang Wang, Qi-Yuan Guan, Pan-Ke Zhang, Jing-Juan Xu*, Hong-Yuan Chen, Synchronized polarization induced electrospray: comprehensively profiling biomolecules in single cells by combining both positive-ion and negative-ion mass spectra[J]. Analytical Chemistry, 2016, 88 (14): 7245-7251.

Contact Us

School of Life Science and Health Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi City, Jiangsu Province, China

E-mail: njuchemhj@126.com & hujun@jiangnan.edu.cn